Hepatobiliary infections (eg, cholangitis) - these can occur without local signs and with only mildly elevated or normal LFTs, especially in the elderly.Previous antibiotic therapy is the most frequent reason for negative blood cultures.Because of their fastidious growth requirements, they have been a frequent cause of culture-negative endocarditis.They are part of the normal oropharyngeal flora, are slow growers and prefer a carbon dioxide-enriched atmosphere.paraphrophilus), Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens and Kingella spp. This is a group of Gram-negative bacilli - Haemophilus spp., ( H.The HACEK group is responsible for 5-10% of cases of infective endocarditis and is the most common cause of Gram-negative endocarditis among people who do not abuse intravenous drugs:. ![]()
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